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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fad435ae92dc992c30cdc23cce7feac5d7215206a19b1b2c8c90ec7894205393' 
  AND token = 'ARWKnwTH1cvzOLX5LLTbS+gbr5uTyQDOwvRnHQ+Uezw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}