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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1445c32de529341f0a3b70534912f586bc827299bee14c95c593639f77da3eb9' 
  AND token = 'o1jnlJKu1Fa2x0d37xrlyAozMiT3MBEPM+LaIo7ykqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}