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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea3f635d624c4056f9bff3141b88b7107e94b78776ef9ec9af3ffb0b678c156' 
  AND token = 'g8wDtn5GGt9fbJh4e/CM5RR0UHNYF5wPLlps0Tp2rR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}