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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e881df6f3b6171757eb363539325584525592e3b88130a0f0e176b674a844d' 
  AND token = '2+9CT7sPPomf75LU0nf439sjoVsD9mIwCtZ87AyJF9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}