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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565448bcbd44c6d5d0b4c0da1cb9697ab88142b01916f5819a5b526b3b4175ef' 
  AND token = 'tzwTIDaVqFds1LxS2Gendezj3QZw2Z/3tpX4sDdKiDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}