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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fbde10c66e498b2e26fe1694962e79a5b3d65f35009ea9c6f218a7edf8dce85' 
  AND token = 'cmc3U5zNdTsDYVx9anQwJRS0l2SqyXXaEA+5kdv5ff4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}