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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef0d606c9badb4746fc7f12153c9b71927174c3db2a6bf92afec5222f1233ae' 
  AND token = '4Q4vlRld9G31psAeGC/CyFYcfYeYNf+OxG1Y+WgC+xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}