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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e49043ffa78e707df08b2a45e20523d54ab5a081b6d465fc005166a80e14315' 
  AND token = 'R3oP4HyaHUGo1wDOXtYI72Pr7cinTh7Jo7N/ujMz5Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}