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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0131a525e11a47fba8ead456f84003a26cd8857520291559b32d948d51a91c7a' 
  AND token = '9DCsQaGYkZh4fsFx9AQhZrTk8GLu784Wd7wxmQ7/t6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}