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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9863b70a70a53cbd1955738c26f78457ae5ac903613dd76a4d131c4c836c459' 
  AND token = 'teK1gJSVH5GxasRS7pUiK5dTqkVvA9Gp4Qe0xbPXDwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}