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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccf48e018a28e44129b33b0a63eaba2daaafa8234ce8378ce178d27ef06a07f7' 
  AND token = 'Kx3TSFlWsdJnvjobEh+hIxmShS62G/t1xFrbBTt26Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}