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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a563d9f84c6b38d9c70f7f9cbb24c0bcce8d67b687fe8e0b5e177f78fb16078c' 
  AND token = 'U7CFjj0fp3ElPw9IEK6Gor7RfG+HmNaY/lcBfAU9vZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}