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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6783e0f7bcfe537a04ac2b5bf163985dd55e995a0ff689b32564410ee9d1dfb' 
  AND token = 'mOGQ9t3m14BuBjxeuugaswYYQL9wLXNIpgo7QLcLs+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}