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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71a833cd7febd838c56e52ae15024f4f4d6016ba91d6c3ad8221fd08fddf7d25' 
  AND token = 'GULBpVdaM1ZuBGpI3hR297Y+4/XETsy7no0T5TMqJw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}