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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a84cd7939eb3fd34013b8fb7ebbe3adc07f2a20b6dcfb32b033edf0d94385b' 
  AND token = 'WXdoVuvNKDeN8jw90vm+4OO75duehtCM9PG+ctiSuUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}