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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7c5db595ad0679003ee299710c18d5d021a6fc527473cc000af6bb02e340232' 
  AND token = 'E71GdURTgzfsjzIKBXEZWNyo6q+3N78dsAgVFDeZ/NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}