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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b072157515280bb35e45545ce11f401692a8d849cf9a81d0aa9368cde6abf11c' 
  AND token = 'm3u+9tTf0HIMu+vMCMZNzzt7IxKFlBeRvB0t9YCW3Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}