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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8ef9dd788a59f79a1177d535267d4960aed82cf10c96bc5237a6d79608743a' 
  AND token = 'HOCjDTBLaidgsKdVkWA+2rbLVDwHbmtVl4um8sGxrhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}