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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22846822aad3034794e338120e9f6ae0274c23d52e5f9f549b38446d0a61625a' 
  AND token = 'n8bYexOdxz9bGTt1nE53A6N26R7sAHHpEyHkWFaPReA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}