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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a530f506546299426755ac8b4ff8bfe2aa3fbf5132a245a6521ce51ca618270' 
  AND token = 'Ot2aPhSFM9GngZzKoGqHWityTrHaB6n0tAEhHE1pfEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}