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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8d998bfadefe6363d0bf54b91e97df442c7d324a4c40f68eaab6553d5a1fa7' 
  AND token = 'C0INHgOpbcnoV89XKAzFK3Z9G7SJJ+5iBvWzSb9M3G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}