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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efb1c51c921d55bd6607bd76fbba656fea93688c8975677119c9be5f46e0054' 
  AND token = '1GUsUJ3nPKUZzl5j+6pMjQfe7rhrAU1mLco1JhmP/P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}