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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d052a5d77e941e1b3e4bf24d9fe8f3b3c87bddf48e7b0307750fb645312170' 
  AND token = 'tqRRff6IafPz97HDZ7LYemfnQ/JL6ylbgOUiA2csOZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}