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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f84d7fed673778b983cd2fc05f9fc414068d06fd2643e4937988d55a4bfa4549' 
  AND token = 'tsH8Eoxiua71JnwSNrsntv6tGFdlycGykCCqc7MQtUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}