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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371ffae9dbcd76d196c23831943aad671213b7192c0dc6318755f71395b05651' 
  AND token = 'I2upjUHEDqTWegA4e34oC55TRQ20EA0bU9oxKqJcsn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}