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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6830f48292ad453fbe1119e253cba3467e4f79c6fd27f7895a12b5905b346b02' 
  AND token = 'fGEpSR35XE9sEJ+vanjsVumzW3233lBn0rhBH3LvMcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}