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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408a3ec06f9b4aae5f84d6eb32bea69b0541235f49fce7555355d48641f9c5b1' 
  AND token = 'YJbgfl8Xjo+Pg+XRn9j6lR+qnKfAD9PUn8m1mgS/S8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}