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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3450fb4f83d7e532e17cfb46a7864407ef9f209eab2b099606372c304cad264' 
  AND token = 'tXnMvWZDmoiA3fpCuUT6D3b7rK47miWQCZK2/0ZCyzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}