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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57848c5fc0608e3ed2c8b3657f6f897518272c98d865f80020c3cbb7f067dbd' 
  AND token = '+PsBYB7UCMTRIVs+ZgcWeVtx/vVAy7Ht+jd8rlIBDA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}