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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a22a60f1e5a5dde61ac3c52afaf68bb70cd55ad7f42916359e98ce1be591397' 
  AND token = 'f/b2vCQ2FXXyr4+vxQGvENfx9Zs74hwUbtSIdCvypEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}