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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bc30e9c1e83da97728dc2552af836025011fdc198548aa3e9b7b9dc15a87a3' 
  AND token = 'VsqUs2B7pvg1U+aW416G29HAxyA1Jhq6tp1QXyb0ZaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}