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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '195dbb81f58cb8e98a03b4302351acd6f2a8e49d8a5d64a7513bdb55534a2133' 
  AND token = 'dr+p52JqXEHIe6hQKppYiAbapG4FokJRLtLLZOLdMxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}