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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c5532adc82e8b77561f163d396e176bb4574abba23b1b17ff7ee7c8807c177' 
  AND token = 'l85we3Z2unoLv/T+oymIC4jLCKBx+ypZaxOjHsjKO8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}