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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58559393f663973e17c3ae27cf8085f981755d05ccf88c83419e416838813475' 
  AND token = 'uO5xnk4CM8aiwRC3xLLnayij6i3boO7nd/giCSqd7Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}