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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd978cb55bfc99fef9799d1023c335d5580f2f76295696760abf6d5ff46086fab' 
  AND token = 'lM4sTbZVNRO8S1vP/3DU8gOMazPm6+DU9iZjK67oMGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}