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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4304fd4bcaa3150ddb8c88b7b40c85963c6a6f6a82e2542520e31956287c73' 
  AND token = 'WmpmL5bW3KGCcNNSSAX16MRfHO/SkxKoJGVYYIrwPTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}