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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecc9f1be9d830b89154a05bc334c286065af87c3796ba2ab66ca911ce20b270' 
  AND token = 'ntuY9tywDn0+csVHJYeHjCP+dSG7f2tdbLyquF9uTYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}