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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0abfe0ed3e2effa6f929b79256b306760758dbf2d4d741fc34fdbc56d5463f' 
  AND token = '7+PUcTLrnFlEo+c4rcpu+2/wmxd5leIfWQIDndrgO2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}