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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4049f60271715202742da4ec13e3212f18aa0f663cac490c6a11ac654b20208' 
  AND token = 'tSr/gnof2GoPVTykdu6MUdAI29OJZQsry8+GfmZ5pYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}