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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86de540b4137cf9aa4911374392185b18a7d22d0f50024dd1c1921509dd1d0d6' 
  AND token = 'ffGijrnYZ0luDsDxkiNhAKunGKuM6K4/2RkKiY3t9GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}