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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e566d29d3d79ec099545df6a5d1cd083d1210e966143e13932be6c61f8022c6' 
  AND token = '5spF/5TPJguoQGLh9bB0RI9yuOPz079WHorehubpH8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}