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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20bbf92e94bd74690eeca9256dfb8d35f6e541b5063f14c674dbe0c4f4f7d45' 
  AND token = '+nxXaMFok5XKKt4RDap9OTr24/PVJ29vxrdJkGxLajE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}