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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865de7c3b9df11e8e83ec784e88205e7ce11a53e0b43ff5ecf7f601a2c934270' 
  AND token = 'p+DDNFdf+9ob/qNaolE470CacxCadE/E9D0nZwX6zV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}