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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c88770d140f3f0634cf5137d112ba6100dd125002c01ae7e4824ba32de7600d9' 
  AND token = 'pEoi0DVrjl9y0G4LRy2zL8S2M3LF0LA4YzvmjJKgMw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}