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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5ebb34e0c0d4c2697c87a3ddef352aa244801d26c61a092df5e78cdfbde183' 
  AND token = 'CPRZe/eHMyqiVsqBIe78gfeJdlIERvjUwN/PlxuYdJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}