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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2a48a1b8626e3720dfef2385b6f9cd8c0e6ee09863586aa367c719701de7f9' 
  AND token = 'DKvHGjhkfPQr2Iw7Ia7NBaHh2b+2LEiM4n1l2Ka18sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}