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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e4ff459205faaa26b62b359f38ac6ea33567999f8d4ba454b272a96a83a167' 
  AND token = 'laMtpeu1qVb8c1C/wYNz81joYk0F55LBCpUUF2rNlRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}