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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5a54f55f807509ed3338dc7f4280b80ee98c95e9a41b34174c1d945f17a969' 
  AND token = 'VxS5GK7cJp49N1NlHkieTBLapnhaQ3PMTac9T3a0WCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}