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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751bc87c3fcf081376e7677e0005685d8e2438ce11c84a1cbf88d4a2fdd0cd8e' 
  AND token = 'PjvHHZufo37+SsWHotldBRvuqudGonTa4Z+S/RWIInc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}