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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ca87c4f2b16ef3406fc36b37a20557d02a5522b832eef63f6848faa431bd40' 
  AND token = 'vg2J02FrueAwiw+Lf/c2kfMFooAp+k5pBrcnzh0MP9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}